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Our Human Strain Probiotics (HSP) Complete 15 provides 7 clinically studied human strains at a potency of 15 billion colony forming units (CFU) per vegetarian capsule. With a balance of probiotics to target the small and large intestinal flora, we have you covered. Unlike enteric coated or delayed release products, our capsules are designed to target the duodenum and exert maximal gut-brain support when taken with food.
Digestive Benefits
HSP Complete 15 is formulated with 2 billion CFU of Lactobacillus acidophilus DDS-1; a strain clinically shown to reduce gastrointestinal discomfort in travel and lactose intolerance. Additionally, this strain has demonstrated an ability to regulate bowel habits and stool consistency. In a double- blind placebo controlled RCT, Bifidobacterium animalis subsp. lactis HN019 was shown to significantly increase frequency of bowel movements in patients struggling with less than 3 movements per week.
Immune System Benefits
In another trial with adults 70 years of age and older, HN019 was shown to increase helper T lymphocyte and natural kill cell activity in patients with low immune response.
In a clinical trial comparing the effectiveness of various probiotic strains on immune responses, groups administered Lactobacillus acidophilus La-14 or Bifidobacterium animalis subsp. Lactis BL-04 were shown to significantly increase serum IgG, compared to controls. In a randomized, double- blind placebo controlled trial, Bifidobacterium animalis subsp. Lactis BL-04 was shown to reduce the incidence of respiratory tract infection and viral shedding after being administered during a rhinovirus infection and supplementing with the probiotic strain for an additional 28 days.
In another double blind placebo controlled trial with 465 healthy adults, Bifidobacterium animalis subsp. Lactis BL-04 (at a dose of 2 billion CFU) was shown to be more effective than placebo and a multi-strain probiotic (19% reduction vs. 27% reduction) in reducing the incidence of respiratory tract infection and improving immunity
Metabolic Benefits
Chronic medical conditions like obesity and hypertension are modifiable cardiometabolic risk factors highly predictive of hospitalization. Our HSP probiotics have been formulated to address the inflammatory biomarkers, hypercholesterolemia, and elevated BMI typically seen in people with reduced immune function. In a randomized double-blind placebo controlled trial with 32 overweight and obese women, our HSP strains were shown to be significantly correlated with BMI, weight, fat mass, lean mass, conicity index, protein intake, monounsaturated fat intake, glycated hemoglobin, TNF-α, and IL6/IL10. The bifidobacteria HSP strains have also demonstrated specific cholesterol absorption properties, leading to decreases in serum total cholesterol and LDL-C.
